Searchable abstracts of presentations at key conferences in endocrinology

ea0050ep073 | Neuroendocrinology and Pituitary | SFEBES2017

Distracting spontaneous refractory hypoglycaemia

Cheah Seong Keat , Rajan Roby , Mathews Abraham , Grant John , Krishnan Singhan , Mathews Anitha , Seshadri Shyam

Case: A 79 years old frail lady with history of dementia and hypertension presented with refractory hypoglycaemia over a period of 3 months requiring multiple admissions. During her most recent admission, she required continuous dextrose infusion to maintain euglycaemia. The severe spontaneous hypoglycaemia in this non-diabetic lady, warranted a series of investigations. TFT and Short Synacthen Test excluded thyroid dysfunction and hypoad...

ea0050ep073 | Neuroendocrinology and Pituitary | SFEBES2017

Distracting spontaneous refractory hypoglycaemia

Cheah Seong Keat , Rajan Roby , Mathews Abraham , Grant John , Krishnan Singhan , Mathews Anitha , Seshadri Shyam

Case: A 79 years old frail lady with history of dementia and hypertension presented with refractory hypoglycaemia over a period of 3 months requiring multiple admissions. During her most recent admission, she required continuous dextrose infusion to maintain euglycaemia. The severe spontaneous hypoglycaemia in this non-diabetic lady, warranted a series of investigations. TFT and Short Synacthen Test excluded thyroid dysfunction and hypoad...

ea0073aep533 | Pituitary and Neuroendocrinology | ECE2021

Improved response to somatostatin analogue (SSA) therapy in acromegaly following treatment pause

Rajan Roby , Bhatt D , Philip S , Graveling AJ , Bashari W , Gurnell M , Abraham P

Background/methodsPatients with uncontrolled acromegaly or receiving high cost medical therapy despite initial treatment, usually transsphenoidal surgery (TSS), were considered for a ¹¹C-methionine PET-CT scan (11C-Met PET-CT). This imaging technique may identify a target for TSS or radiotherapy when MRI appearances are inconclusive1. In preparation, four patients on long-term SSA were taken off treatment 3 months prior to the scan. ...

ea0077p20 | Adrenal and Cardiovascular | SFEBES2021

Adrenal Incidentaloma Pathway - A four-year experience at a teaching hospital

Rajan Roby , Chandy Shekinah Grace K M , Radhakrishnan Parvathy , Paterson Rachel , Aspinall Sebastian , Graveling Alex J , Philip Sam , Abraham Prakash

Background /Methods: Adrenal incidentalomas pose a significant burden to endocrinology services in assessing the clinical significance of these lesions. Following vetting of the incidentaloma referrals, the patients at our centre are initially seen in a nurse-led clinic for biochemical investigations and to ensure completion of radiology assessment using a structured proforma. This step facilitates efficient patient flow and quicker decision making. The clinical outcomes of th...

ea0073yi4 | Young Investigator Awards | ECE2021

Use of 11C-methionine PET-CT scanning to guide management of acromegaly following primary therapy – A pragmatic prioritisation strategy to achieve maximal cost effectiveness

Rajan Roby , Bhatt D , Philip S , Graveling AJ , Kamel M , Olson S , Mckiddie F , Gillett D , Bashari W , Gurnell M , Abraham P

Background11C-methionine (11C-Met) positron emission tomography co-registered with MRI is a new imaging technique used for functioning pituitary adenomas, permitting targeted intervention (Transphenoidal Surgery (TSS) or Radiotherapy)1. The 11C-Met PET-CT scan has been available in our centre since Dec 2016. With limited availability in 2019/2020 (due to cyclotron refurbishment) we re-audited our patients to prioritise th...